Three seats, three ways to play medium hands
In position (CO, BTN). Keep the same value. Drop the offsuit bluffs and cut the suited bluffs by about a quarter. Pairs and suited hands would rather call: you will play the flop with position. That holds from 50bb up. At 25bb only pairs 77+ and suited broadways flat (BTN against a HJ open: 99 to 77, AJs, ATs, KQs, KJs, KTs, QJs, QTs, JTs); at 15 to 20bb it is shove or fold.
From the SB. Squeeze or fold, almost never call. The BB behind you can still raise, and you would play out of position against two players. Squeeze at the top size (6 to 6.5 times the open).
In the BB. You close the action at a good price. From 50bb up, suited connectors, small pairs and suited one-gappers call instead of squeezing. At 25bb, 22 to 66, 54s, Q9s and the one-gappers J9s to 64s fold; at 15 to 20bb the BB flats only 77+, suited aces and suited broadways, so T9s to 65s stop calling too.